No effect of honey on intestinal and hepatic CYP3A
It’s suggested that honey may stimulate the CYP3A enzyme, and this might alter the metabolism of drugs. Researchers in Germany studied the effect of repeated honey administration on human CYP3A enzyme...
View ArticleInteraction between Shengmai-yin and warfarin
Shengmai-yin (Sheng Mai Yin Pian) is a concentrated Chinese herbal medicine used to “treat a deficiency of vital energy and Yin, palpitation and shortness of breath, faint pulse, and spontaneous...
View ArticleInteraction between aliskiren and fruit juice
Aliskiren (Tekturna) is used to treat high blood pressure. It’s poorly absorbed from the intestines (about 2.5%). Researchers at Helsinki University Central Hospital, in Finland, report that apple and...
View ArticleDo we overhype drug-supplement interactions?
Real and hypothetical concerns exist. Dr. Mark Moyad (photo), who is Director of Preventive and Alternative Medicine at the University of Michigan Medical Center in Ann Arbor, puts it into perspective....
View ArticleLowering drug blood levels with grapefruit juice: When’s it significant?
Ask about the grapefruit/drug interaction and most people think of the increased blood levels of statins when grapefruit is eaten before taking a dose. Now, Dr. David Bailey at the University of...
View ArticleThe final word on the warfarin-cranberry interaction?
“The warning that there is a potential to enhance the effect of warfarin… with cranberry juice intake is mostly based on faulty reports.” That’s the conclusion by researchers at Lenox Hill Hospital, in...
View ArticleDoes Echinacea interact with HIV drugs?
Not much, according to researchers in Spain. First, the details. 15 HIV-infected adults receiving antiretroviral therapy including darunavir/ritonavir (Prezista/Norvir) (600/100 mg twice daily) for at...
View ArticleUse of herbal supplements by people taking blood thinners
During the American Heart Association meeting, Dr. Jennifer Strohecker, at the Intermountain Medical Center, in Salt Lake City, Utah, reported that documentation of supplement use in the medical chart...
View ArticleDrug interactions with St John’s wort
It’s a long list compiled by researchers at RMIT University in Victoria, Australia. Anticancer agents: imatinib (Gleevec) and irinotecan (Camptosar) Anti-HIV agents: eg, indinavir (Crixivan),...
View ArticleMarijuana interaction with warfarin reported
Researchers from the Cheyenne Veterans Affairs Medical Center, in Wyoming report that when taken together, 1 patient experienced bleeding from the blood “thinner” warfarin (Coumadin). First, the...
View ArticleGrapefruit interaction with tolvaptan
Tolvaptan (Samsca) is used to treat hyponatremia — too little sodium in the blood. Patients with heart failure, liver problems (eg, cirrhosis), and the syndrome of inappropriate antidiuretic hormone...
View ArticleRisk of drug interactions with dietary supplements
Researchers in the US reviewed the incidence and severity of potential interactions between prescription medicine and dietary supplements. First, the details. A survey was conducted on dietary...
View ArticleFinal word on the statin-grapefruit juice interaction?
Researchers at Tufts University School of Medicine and Tufts Medical Center, in Boston, are the first to evaluate changes in the cholesterol-lowering effects of atorvastatin (Lipitor) in patients with...
View ArticlePotential for berberine to cause drug interactions
Berberine is used to treat gastrointestinal infections, diabetes, high blood pressure, and cholesterol. Many studies report interactions between berberine-containing products and cytochrome P450, but...
View ArticleExpanding the list of drugs that interact with grapefruit juice
Dr. David Bailey from the University of Western Ontario in London, Canada, reported the “grapefruit effect” more than 15 years ago. Now, Dr. Bailey and coworkers at the University of Western Ontario...
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